Nitrofurantoin: study card

Generic name

Nitrofurantoin

Class

Nitrofuran urinary antibacterial

Mechanism

Reduced by bacterial flavoproteins to reactive intermediates that damage ribosomal proteins and inhibit protein, DNA, RNA and cell wall synthesis.

Used for

Urinary tract infections (susceptible strains)

Common side effects

Pulmonary hypersensitivity reactions; Hepatic reactions (rare)

Warnings

Contraindicated in significant renal impairment; Contraindicated at term pregnancy and in neonates; Prior nitrofurantoin cholestatic jaundice; The source excludes pyelonephritis and perinephric abscesses from its indications

Interactions

Magnesium trisilicate antacids; Probenecid / sulfinpyrazone

Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.

Label date: 20260717 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.