Hydralazine — Direct-acting arterial vasodilator. Study the mechanism, listed uses and warnings from the US label on one sourced card.
Generic name
Hydralazine
Class
Direct-acting arterial vasodilator
Mechanism
The precise mechanism is incompletely understood; hydralazine apparently lowers blood pressure through direct vascular smooth-muscle relaxation and altered cellular calcium handling, preferentially dilating arterioles.
Coronary artery disease (contraindicated); Mitral valvular rheumatic heart disease (contraindicated); A lupus-like syndrome, sometimes involving glomerulonephritis, can occur
Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.
Label date: 20260908 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: Inhibits HMG-CoA reductase, the rate-limiting enzyme converting HMG-CoA to mevalonate, a precursor of cholesterol.
On both cards: Common side effects — Headache; Nausea
Only on the Rosuvastatin card: Used for — As an adjunct to diet to lower LDL cholesterol in adults with primary hyperlipidemia and to slow atherosclerosis progression in adults; Reduction of major cardiovascular events in adults without established coronary disease who meet the label's age, hsCRP of at least 2 mg/L and additional-risk-factor criteria; Heterozygous familial hypercholesterolemia in adults and children aged 8 years and older, as an adjunct to diet; Homozygous familial hypercholesterolemia in adults and children aged 7 years and older, with other LDL-lowering treatment or alone when unavailable · Common side effects — Myalgia; Asthenia; Constipation · Warnings — Myopathy / rhabdomyolysis; Immune-mediated necrotizing myopathy; Acute liver failure or decompensated cirrhosis
Mechanism: Prodrug hydrolyzed to simvastatin acid, which inhibits HMG-CoA reductase, the rate-limiting enzyme of cholesterol synthesis.
On both cards: Common side effects — Headache; Nausea
Only on the Simvastatin card: Used for — Reduction of coronary death, nonfatal MI, stroke or revascularization need in high-risk adults with the established vascular disease or diabetes described in the label; As an adjunct to diet to lower LDL cholesterol in adults with primary hyperlipidemia or in adults and children aged 10 years and older with heterozygous familial hypercholesterolemia; As an adjunct to other LDL-lowering treatment in adults with homozygous familial hypercholesterolemia; As an adjunct to diet for hypertriglyceridemia in adults · Common side effects — Upper respiratory infection; Abdominal pain; Constipation · Warnings — Myopathy / rhabdomyolysis; Immune-mediated necrotizing myopathy; Acute liver failure or decompensated cirrhosis
On both cards: Common side effects — Headache; Nausea
Only on the Triamterene / Hydrochlorothiazide card: Used for — Hypertension or edema with hypokalemia on HCTZ; Thiazide need where hypokalemia can't be risked · Common side effects — Dizziness; Fatigue; Dry mouth · Warnings — Hyperkalemia (contraindicated); Other potassium-conserving agents or supplements; Anuria / significant renal impairment
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.
Capsera