Fenofibrate: study card

Generic name

Fenofibrate

Class

PPAR-alpha agonist (fibrate)

Mechanism

Fenofibric acid activates PPAR-alpha, increasing lipoprotein lipase activity and lowering apo C-III, which reduces triglyceride-rich particles.

Used for

Primary hypercholesterolemia or mixed dyslipidemia in adults, as an adjunct to diet; Severe hypertriglyceridemia in adults, as an adjunct to diet

Common side effects

Abnormal liver tests; Increased AST / ALT; Increased CPK; Rhinitis

Warnings

Hepatotoxicity; Myopathy / rhabdomyolysis (risk higher with statins); Cholelithiasis

Interactions

Coumarin anticoagulants; Immunosuppressants; Bile acid resins

Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.

Label date: 20260730 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.