Ezetimibe — Cholesterol absorption inhibitor (NPC1L1). Study the mechanism, listed uses and warnings from the US label on one sourced card.
Generic name
Ezetimibe
Class
Cholesterol absorption inhibitor (NPC1L1)
Mechanism
Blocks the NPC1L1 sterol transporter at the intestinal brush border, reducing cholesterol absorption and hepatic delivery.
Used for
Primary hyperlipidemia in adults, with diet and a statin or alone when additional LDL-lowering therapy is not possible; Heterozygous familial hypercholesterolemia from age 10, with diet and a statin; Mixed hyperlipidemia in adults, with diet and fenofibrate; Homozygous familial hypercholesterolemia from age 10, with a statin and other LDL-lowering therapy; Homozygous familial sitosterolemia from age 9, as an adjunct to diet
Liver enzyme elevations; Myopathy / rhabdomyolysis; Risks of combined statin or fenofibrate
Interactions
Cyclosporine; Fibrates; Bile acid sequestrants
Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.
Label date: 20260706 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: Selectively and competitively inhibits HMG-CoA reductase, a key enzyme in cholesterol synthesis. In animal models, increased hepatic LDL receptors also contribute to LDL uptake and breakdown.
On both cards: Common side effects — Diarrhea; Arthralgia · Warnings — Myopathy / rhabdomyolysis
Only on the Atorvastatin card: Used for — As an adjunct to diet to lower LDL cholesterol in adults with primary hyperlipidemia or in adults and children aged 10 years and older with heterozygous familial hypercholesterolemia; Reduction of specified cardiovascular events in adults with established coronary heart disease or the multiple coronary risk factors described in the label; Homozygous familial hypercholesterolemia in adults and children aged 10 years and older, with other LDL-lowering treatment or alone when that treatment is unavailable · Common side effects — Nasopharyngitis; Pain in extremity; Urinary tract infection · Warnings — Immune-mediated necrotizing myopathy; Acute liver failure or decompensated cirrhosis · Interactions — Cyclosporine, gemfibrozil, grapefruit juice; Rifampin; Digoxin
Mechanism: Reversibly inhibits HMG-CoA reductase, the rate-limiting enzyme converting HMG-CoA to mevalonate, a cholesterol precursor.
On both cards: Common side effects — Diarrhea · Warnings — Myopathy / rhabdomyolysis · Interactions — Cyclosporine
Only on the Pravastatin card: Used for — Adjunct to diet for primary hyperlipidemia in adults, or heterozygous familial hypercholesterolemia in children aged 8 years and older; Reduction of myocardial infarction, revascularization and cardiovascular death in adults with elevated LDL-C without clinically evident coronary heart disease; Reduction of specified coronary/cerebrovascular events and slowing coronary atherosclerosis in adults with clinically evident coronary heart disease; Adjunct to diet for hypertriglyceridemia or primary dysbetalipoproteinemia in adults · Common side effects — Musculoskeletal pain; Nausea / vomiting; Upper respiratory infection; Headache · Warnings — Immune-mediated necrotizing myopathy; Hepatic dysfunction · Interactions — Gemfibrozil; Clarithromycin / erythromycin
Mechanism: Blocks angiotensin II at the AT1 receptor, reducing vasoconstriction and aldosterone release.
On both cards: Common side effects — Diarrhea; Sinusitis
Only on the Telmisartan card: Used for — Hypertension in adults; Reduction of myocardial infarction, stroke or cardiovascular death risk in adults aged 55 years and older at high cardiovascular risk who cannot take ACE inhibitors · Common side effects — Back pain · Warnings — Hypotension; Hepatic or renal impairment; Avoid combining ACE inhibitor with ARB · Interactions — Aliskiren; Digoxin; Ramipril
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.
Capsera