Cyproheptadine: study card

Generic name

Cyproheptadine

Class

Antihistamine / antiserotonergic agent

Mechanism

Serotonin and histamine antagonist with anticholinergic and sedative effects; these drugs appear to compete with serotonin and histamine at receptor sites.

Used for

Perennial or seasonal allergic rhinitis (age 2 and older); Allergic conjunctivitis caused by inhalant or food allergens (age 2 and older); Mild, uncomplicated allergic urticaria or angioedema (age 2 and older); Cold urticaria or dermatographism (age 2 and older)

Common side effects

Reported with antihistamines: sedation, sleepiness and dizziness; Reported with antihistamines: dry mouth; Reported with antihistamines: increased appetite or weight gain

Warnings

Contraindicated in newborn or premature infants and nursing mothers; Contraindicated in angle-closure glaucoma or symptomatic prostatic hypertrophy; Pediatric antihistamine overdose may cause hallucinations, seizures, respiratory or cardiac arrest, and death

Interactions

MAOIs (intensified anticholinergic effects); Alcohol and other CNS depressants

Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.

Label date: 20260820 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.