Cetirizine — Second-generation H1 antihistamine. Study the mechanism, listed uses and warnings from the US label on one sourced card.
Generic name
Cetirizine
Class
Second-generation H1 antihistamine
Mechanism
Metabolite of hydroxyzine; selective peripheral H1-receptor antagonist.
Used for
Hay fever: runny nose, sneezing; Itchy, watery eyes
Common side effects
Drowsiness; Itching after stopping (rare)
Warnings
Allergy to hydroxyzine; Liver or kidney disease: dose review; Drowsiness can impair driving; alcohol, sedatives and tranquilizers can increase it; Itching can occur after cetirizine is stopped; the selected label advises contacting a healthcare professional
Interactions
Alcohol; Sedatives and tranquilizers
Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.
Label date: 20260825 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: The active enantiomer of cetirizine selectively inhibits H1 receptors. In vitro, its human H1-receptor affinity was about twice that of cetirizine; the clinical relevance of this comparison is unknown.
Only on the Levocetirizine card: Used for — Uncomplicated skin manifestations of chronic idiopathic urticaria in adults and children aged 6 or older · Common side effects — Somnolence; Nasopharyngitis; Fatigue; Dry mouth; Pharyngitis · Warnings — Somnolence; avoid alcohol and CNS depressants; Urinary retention; Pruritus after discontinuation · Interactions — Alcohol / CNS depressants
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.