Anastrozole: study card

Generic name

Anastrozole

Class

Aromatase inhibitor

Mechanism

Inhibits aromatase, blocking conversion of adrenal androgens to estrone and estradiol in postmenopausal women.

Used for

Adjuvant treatment of hormone receptor-positive early breast cancer in postmenopausal women; First-line treatment of hormone receptor-positive or receptor-unknown locally advanced or metastatic breast cancer in postmenopausal women; Advanced breast cancer in postmenopausal women after progression on tamoxifen

Common side effects

Hot flashes; Asthenia; Arthralgia; Hypertension; Depression

Warnings

More ischemic cardiovascular events than with tamoxifen in women with pre-existing ischemic heart disease; Decreased bone mineral density; Increased cholesterol

Interactions

Tamoxifen; Estrogen-containing products

Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.

Label date: 20260820 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.